Nanoelectronics Meets Biology: From New Nanoscale Devices for Live-Cell Recording to 3D Innervated Tissues

Nanoelectronics meets biology: from new nanoscale devices for live-cell recording to 3D innervated tissues.

High spatiotemporal resolution interfaces between electrical sensors and biological systems, from single live cells to tissues, is crucial for many areas, including fundamental biophysical studies as well as medical monitoring and intervention. Herein, we summarize recent progress in the development and application of novel nanoscale devices for intracellular electrical recording of action pote...

Nanoelectronics-biology frontier: From nanoscopic probes for action potential recording in live cells to three-dimensional cyborg tissues.

Semiconductor nanowires configured as the active channels of field-effect transistors (FETs) have been used as detectors for high-resolution electrical recording from single live cells, cell networks, tissues and organs. Extracellular measurements with substrate supported silicon nanowire (SiNW) FETs, which have projected active areas orders of magnitude smaller than conventional microfabricate...

Supplementary Information for: Three-dimensional mapping and regulation of action potential propagation in nanoelectronics innervated tissues

Three-dimensional mapping and regulation of action potential propagation in nanoelectronics innervated tissues

Real-time mapping and manipulation of electrophysiology in three-dimensional (3D) tissues could have important impacts on fundamental scientific and clinical studies, yet realization is hampered by a lack of effective methods. Here we introduce tissue-scaffold-mimicking 3D nanoelectronic arrays consisting of 64 addressable devices with subcellular dimensions and a submillisecond temporal resolu...

Synthetic meets cell biology

Following a successful panel discussion at last years' American Society for Cell Biology Annual Meeting, the first minisymposium in Synthetic Cell Biology was held at this years' annual meeting in Denver. This is an exciting first for the society, and the attendance clearly supported the interest of cell biologists in applying the concepts of synthetic biology to the understanding and engineeri...